Frequently Asked Questions About Pheochromocytoma and Paraganglioma

What is pheochromocytoma?

Pheochromocytoma is a rare tumor originating in the adrenal glands, specifically, the medulla of adrenal glands. Pheochromocytoma-related signs and symptoms are caused by the presence of an excess amount of hormones called catecholamines. These hormones include norepinephrine (noradrenaline), epinephrine (adrenaline), and rarely a very high amount of dopamine.

What is paraganglioma?

Paraganglioma is a tumor that is closely related to pheochromocytoma. It originates from outside the adrenal glands, specifically from the parasympathetic or sympathetic nervous system. Paragangliomas are much less common than pheochromocytomas. Just like pheochromocytoma, paraganglioma-related signs and symptoms are also caused by the presence of an excess amount of catecholamines.